The primary conflict is driven by , who kidnaps Dean’s former girlfriend, Lisa Braeden , and her son, Ben , to force the Winchesters to stop their pursuit of Purgatory.

Suffers possession and a near-fatal injury before her memory is wiped.

Faces increasing tension with the Winchesters; heals Lisa but captures Eleanor. Lisa Braeden

Betrays Castiel's plans to help the brothers find Crowley’s warehouse.

During the rescue, Dean discovers Lisa is possessed by a demon. In a harrowing sequence, the demon-possessed Lisa stabs herself with a razor to taunt Dean.

Parallel to the rescue, Bobby investigates the origin of the current threat, leading to a historical mystery involving horror author .

The investigation reveals that Bobby’s longtime friend and mentor, Dr. Eleanor Visyak , is actually the creature that crossed over from Purgatory during Lovecraft's ritual. Castiel eventually captures her to obtain the blood needed to reopen the door. Cast and Key Players Role in Episode Jensen Ackles Dean Winchester

While Castiel eventually heals her physical wounds at the hospital, Dean realizes his world will never be safe for them. He has Castiel wipe their memories of him entirely, a decision that leaves Dean devastated and Sam deeply angry. Secondary Plot: H.P. Lovecraft and Purgatory