Locked In Apr 2026

Locked-in Syndrome (LiS) is a rare neurological disorder where a patient is fully conscious and aware but experiences complete paralysis of nearly all voluntary muscles, except for those controlling vertical eye movements and blinking. This condition is most commonly caused by damage to the in the brainstem, often resulting from a stroke or vascular injury. Core Characteristics

According to the National Institute of Neurological Disorders and Stroke , LiS is defined by:

While stroke is the leading cause (specifically basilar artery occlusion), other factors can trigger the syndrome: Case Report and Discussion of Decisional Capacity

: Full alertness, cognitive function, and the ability to think and reason.

: Quadriplegia (paralysis of all four limbs) and the inability to move the face or body. Anarthria : The complete loss of articulate speech.

: The primary mode of communication is typically through vertical eye movements and blinking. Common Causes

According to the National Institute of Neurological Disorders and Stroke , LiS is defined by: Locked In

While stroke is the leading cause (specifically basilar artery occlusion), other factors can trigger the syndrome: Case Report and Discussion of Decisional Capacity Locked-in Syndrome (LiS) is a rare neurological disorder

: Full alertness, cognitive function, and the ability to think and reason. : Quadriplegia (paralysis of all four limbs) and

: Quadriplegia (paralysis of all four limbs) and the inability to move the face or body. Anarthria : The complete loss of articulate speech.

: The primary mode of communication is typically through vertical eye movements and blinking. Common Causes