Dnaddr.mica_p-1-10.1.var Apr 2026

Variations in the MICA gene, including the P-1-10.1.var lineage, are significant in several medical contexts:

: These segments typically denote the specific position of the variation within the protein sequence or a versioned entry in a genomic assembly [4, 5]. Clinical and Biological Significance Dnaddr.Mica_P-1-10.1.var

: MICA antibodies are a known factor in the rejection of kidney and heart transplants. Discrepancies between the donor's and recipient's MICA variants can trigger an immune response [6]. Variations in the MICA gene, including the P-1-10

is a specific genetic variant identifier associated with the MICA (MHC class I polypeptide-related sequence A) gene . This nomenclature is primarily used in specialized genomic databases to catalog variations in the MICA protein, which plays a critical role in the human immune system's ability to detect stressed or infected cells. Core Function of the MICA Gene is a specific genetic variant identifier associated with

: MICA serves as a ligand for the NKG2D receptor , which is found on Natural Killer (NK) cells and certain T cells [1, 2].