Atopy [ Working CHOICE ]

: Sensitization through inflamed skin can lead to early-onset food allergies.

: Antigen-presenting cells perceive allergens (like pollen or dust mites) as danger signals, activating TH2 or ILC2 cells. : Sensitization through inflamed skin can lead to

: Systemic immune priming eventually leads to upper and lower airway inflammation. 3. Key Management Strategies caused by skin barrier defects (e.g.

Atopy typically follows a predictable chronological progression: : Sensitization through inflamed skin can lead to

: Often the first sign in infancy, caused by skin barrier defects (e.g., filaggrin mutations) that allow for epicutaneous allergen sensitization.